
01 · Vial
02 · Label
03 · PackagingN° 001Catalog Entry
Retatrutide
RETA · GLP-3 · LY3437943
Triple agonist · GLP-1 / GIP / glucagon receptors
Research-use-only catalog item supplied for laboratory identification and research purposes. Not for human consumption.
Description
A synthetic peptide investigational agonist at the GLP-1, GIP, and glucagon receptors. Supplied as a lyophilized research-use-only reference compound.
Retatrutide is a long-acting synthetic peptide designed to simultaneously activate the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIP-R), and the glucagon receptor (GCGR). The combined triple-agonist profile drives downstream signaling that links incretin-mediated insulin response with hepatic and adipose energy metabolism.
N° 002 — Mechanism of Action
How Retatrutide acts at the molecular level.
Retatrutide is a long-acting synthetic peptide designed to simultaneously activate the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIP-R), and the glucagon receptor (GCGR). The combined triple-agonist profile drives downstream signaling that links incretin-mediated insulin response with hepatic and adipose energy metabolism.
N° 003 — Areas of Active Research
Where Retatrutide appears in the literature.
Reference areas in which Retatrutide is investigated as a research tool. Listed for catalog context only — Superb Peptides does not provide medical, dosing, or human-use guidance.
- 01Preclinical and clinical models of obesity and excess adiposity
- 02Glucose homeostasis and type 2 diabetes models
- 03Hepatic lipid metabolism and MASH/NASH investigations
- 04Energy expenditure and substrate utilization studies
N° 004 — Reference Data
Catalog specifications.
Molecular and structural reference data for this catalog entry. COA placeholders and batch identifiers are tracked internally and available on request.
Molecular Spec Sheet
Edition · 2026
- Catalog ID
- SP-RETATRUTIDE-10
- Molecular Weight
- ≈ 4 731 Da
- Empirical Formula
- C221H343N53O68
- CAS Number
- 2381089-83-2
- Sequence Note
- 39-residue synthetic peptide bearing a C20 diacid lipid moiety
- Storage
- 2–8°C, protect from light
- Intended Use
- Laboratory research only
N° 005 — Lab Handling
Reconstitution & storage notes.
- 01Reconstitute in bacteriostatic or sterile water for in-vitro reference work
- 02Once reconstituted, aliquot to minimise freeze–thaw cycles
- 03Store lyophilized vial at 2–8°C; long-term storage at −20°C
All products are intended strictly for laboratory research use only. Not for human consumption. Not for medical, diagnostic, therapeutic, veterinary, or household use. Product information is provided for research identification and catalog purposes only.
N° 006 — Related
More from the catalog.



GHK-Cu
