
01 · Vial
02 · Label
03 · PackagingN° 001Catalog Entry
MOTS-c
Mitochondrial Open Reading Frame of 12S rRNA-c
Mitochondrial-derived peptide · AMPK pathway
Research-use-only catalog item supplied for laboratory identification and research purposes. Not for human consumption.
Description
A 16-residue mitochondrial-derived peptide encoded within the 12S rRNA gene. Reference compound for studies of cellular energy regulation.
MOTS-c is a mitochondrially-encoded peptide that translocates to the nucleus under metabolic stress and modulates AMPK signaling, folate–methionine cycle intermediates, and adaptive nuclear gene expression. It links mitochondrial status with systemic metabolic homeostasis.
N° 002 — Mechanism of Action
How MOTS-c acts at the molecular level.
MOTS-c is a mitochondrially-encoded peptide that translocates to the nucleus under metabolic stress and modulates AMPK signaling, folate–methionine cycle intermediates, and adaptive nuclear gene expression. It links mitochondrial status with systemic metabolic homeostasis.
N° 003 — Areas of Active Research
Where MOTS-c appears in the literature.
Reference areas in which MOTS-c is investigated as a research tool. Listed for catalog context only — Superb Peptides does not provide medical, dosing, or human-use guidance.
- 01Insulin sensitivity and glucose disposal in skeletal muscle models
- 02Exercise physiology and adaptive metabolic capacity
- 03Mitochondrial dysfunction and ageing biology
- 04Adipose tissue energy partitioning studies
N° 004 — Reference Data
Catalog specifications.
Molecular and structural reference data for this catalog entry. COA placeholders and batch identifiers are tracked internally and available on request.
Molecular Spec Sheet
Edition · 2026
- Catalog ID
- SP-MOTSC-10
- Molecular Weight
- ≈ 2 174 Da
- Empirical Formula
- C100H152N28O22S2
- Sequence
- MRWQEMGYIFYPRKLR
- Sequence Note
- 16 residues, mitochondrial-encoded
- Storage
- 2–8°C, protect from light
- Intended Use
- Laboratory research only
N° 005 — Lab Handling
Reconstitution & storage notes.
- 01Reconstitute in sterile water at desired working concentration
- 02Aliquot and freeze at −20°C for long-term storage
- 03Avoid repeat freeze–thaw cycles
All products are intended strictly for laboratory research use only. Not for human consumption. Not for medical, diagnostic, therapeutic, veterinary, or household use. Product information is provided for research identification and catalog purposes only.
N° 006 — Related
More from the catalog.



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